Harness the future of PV with Krrch's unparalleled AI. Extract critical safety intelligence from medical literature with unprecedented speed, accuracy, and insight.
Our platform integrates deeply with your workflow, offering a suite of AI-driven tools for comprehensive literature surveillance and safety signal management.
Proprietary NLP models, fine-tuned on biomedical corpora, discern ADRs, events, and drug mentions with industry-leading precision and recall.
Go beyond keyword spotting. Krrch's AI understands sentence structure and context to assess the likelihood of causality between drugs and events described in literature.
Identify emerging safety signals and disproportionality trends earlier. Visualize event frequencies, co-occurrences, and IME/DME patterns across vast datasets.
Krrch provides specialized tools and workflows for diverse PV tasks, empowering teams of all sizes.
Move beyond reactive safety monitoring. Krrch helps you systematically scan literature for emerging adverse event trends, potential drug-drug interactions, and events in special populations.
Enhance the quality and completeness of Individual Case Safety Reports. Krrch rapidly identifies published case reports or relevant studies related to events in your safety database.
Simplify the literature search and review component of PSURs, PBRERs, and DSURs. Krrch helps identify relevant publications for inclusion, summarize key findings, and track safety topics over time.
Empower QPPVs and safety teams with continuous, systematic literature surveillance. Krrch helps ensure no critical safety information is missed, supporting regulatory compliance and proactive risk management.
Krrch transforms complex literature analysis into an intuitive, AI-accelerated process.
Define precise search parameters: drug names, combinations, adverse event terms (MeSH, MedDRA), date ranges, and article types. Krrch queries PubMed and can integrate other sources (Enterprise) for comprehensive coverage.
Our advanced Natural Language Processing engine meticulously analyzes retrieved articles. It identifies drug mentions, extracts potential ADRs, recognizes event types (IME, DME), and pinpoints attributary statements for causality clues.
Explore results in Krrch's intuitive interface. View highlighted abstracts, sortable tables of extracted events, causality indicators, and dynamic charts visualizing trends. Filter, refine, and validate with ease.
Export curated data for ICSRs, signal validation reports, or aggregate safety assessments. Krrch provides the auditable evidence base to support your critical pharmacovigilance decisions and regulatory obligations.
Beyond our core literature intelligence, Krrch offers dedicated applications to enhance specific pharmacovigilance workflows. These tools require login and an active Krrch account status for access.
Dive deep into USFDA FAERS data. Analyze specific drugs, identify reporting trends, calculate Relative Reporting Frequencies (RRF), visualize top adverse events, and explore potential signals within your defined review periods.
Launch FAERS ExplorerEfficiently cross-reference PubMed articles with FAERS literature case references. Identify potential ICSRs sourced from literature for specific drugs and review periods, streamlining your literature surveillance and case processing tasks.
Launch Literature LinkerDiscover what sets Krrch apart in the landscape of PV literature intelligence solutions.
Our AI models are specifically trained on vast biomedical literature and pharmacovigilance terminologies, ensuring superior accuracy in ADR and causality extraction over generic NLP tools.
Dramatically reduce manual review burdens. Krrch processes thousands of articles, presenting structured, actionable data in minutes, freeing your experts for high-value analysis.
Built by PV professionals, for PV professionals. An intuitive interface, customizable dashboards, and seamless workflow integration make Krrch easy to adopt and powerful to master.
Krrch supports your GVP compliance with features like detailed search histories, transparent data sourcing, and exportable results for your audit trail (Enterprise Tier).
Choose a plan that scales with your organization's needs, from individual exploration to enterprise-wide pharmacovigilance transformation.
Begin your journey into AI-powered literature review. Ideal for individual use and basic exploration.
Comprehensive AI toolkit for dedicated PV teams focused on efficiency and robust signal detection.
Bespoke AI, integration, and compliance for large-scale, global pharmacovigilance operations.
All plans include access to Krrch's core PubMed search functionality. Additional tools (FAERS Explorer, Literature Linker) are available to active account holders. Learn more in our FAQ.
Krrch employs state-of-the-art NLP models specifically trained on vast corpora of biomedical text and PV-specific terminologies. While accuracy can vary based on text complexity and quality, our models consistently achieve high precision and recall rates (often exceeding 90%) for key ADR entity recognition and relationship extraction. We continuously refine our algorithms based on new research and real-world performance data.
Our core literature screening tool primarily integrates with NCBI PubMed. The FAERS Signal Explorer and PubMed-FAERS Literature Linker tools utilize data from the openFDA API, specifically the Adverse Event Reporting System (FAERS) database. Enterprise versions can be customized to incorporate other internal or licensed literature databases, and potentially full-text article feeds where available and permissible.
Krrch is designed as a tool to support GVP (Good Pharmacovigilance Practices) compliance. Features such as traceable search histories, versioned outputs (Enterprise), and transparent data sourcing aid in audit readiness. Regarding data privacy, Krrch processes publicly available literature data (PubMed, openFDA) or data provided by your organization under your governance policies. We adhere to stringent data security protocols. Specific compliance certifications and GxP validation packages can be discussed for Enterprise deployments.
The Explorer Free tier allows you to experience Krrch's core PubMed literature screening functionality and basic event highlighting on a limited number of articles per search. Paid plans (PV Professional and Enterprise Suite) unlock unlimited article processing, full NLP-driven ADR and causality analysis, advanced analytics dashboards, comprehensive data export options, custom watchlists, team collaboration features, and dedicated support. Access to specialized tools like the FAERS Signal Explorer and PubMed-FAERS Literature Linker is typically included with active paid subscriptions but may have usage quotas depending on the plan.
Yes, the Krrch Enterprise Suite offers API capabilities for integration with leading safety databases. This can facilitate seamless data flow, such as pushing potential signals or relevant literature case findings from Krrch into your safety system for further case processing, signal management workflows, or to enrich existing case data. Custom integration projects can also be scoped based on specific requirements.
Connect with our specialists to explore how Krrch can integrate with your existing systems and elevate your pharmacovigilance capabilities to the next frontier.